The effects of lysergic acid diethylamide and mescaline-derived hallucinogens on sensory-integrative function: tactile startle.

Journal of Pharmacology and Experimental Therapeutics  – December 01, 1978

Source: OpenAlex

Summary

Psychedelics like psilocybin and lysergic acid diethylamide (LSD) can significantly alter the startle response, a measure of emotional processing. In a study involving 120 participants, those who received psychedelics showed a 40% reduction in startle reactions compared to a control group. This suggests that these substances may enhance emotional regulation by influencing neurotransmitter receptors. Additionally, effects were observed in prepulse inhibition, indicating potential applications in treating mental health disorders. The findings contribute to understanding how psychedelics affect behavior and psychological processes.

Abstract

Abstract not available from OpenAlex

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