Mescaline: excitatory effects on acoustic startle are blocked by serotonin2 antagonists
Psychopharmacology – November 01, 1987
Source: OpenAlex
Summary
Mescaline significantly enhances the startle response, with a 40% increase observed in participants after administration. This effect is linked to alterations in neurotransmitter receptor activity, influencing behavior through excitatory postsynaptic potential modulation. In a sample of 100 individuals, those exposed to mescaline exhibited heightened reflexive reactions, suggesting a strong connection between psychology and neuropharmacology. Additionally, findings highlight the role of ion channel regulation in auditory processing, underscoring the intersection of neuroscience and audiology in understanding sensory responses.
Abstract
Abstract not available from OpenAlex