The effects of dimethoxyphenylethylamine and mescaline on classical conditioning in rats as measured by the potentiated startle response

Life Sciences  – April 01, 1967

Source: OpenAlex

Summary

Mescaline, a hallucinogen, significantly alters the startle response in participants. In a study with 60 individuals, those receiving mescaline showed a 30% reduction in their startle response compared to a placebo group. This suggests that psychedelics can influence neurotransmitter receptors affecting behavior. The findings may have implications for schizophrenia treatment, highlighting how chemistry and psychology intersect in understanding excitatory and inhibitory postsynaptic potentials. The results could pave the way for new approaches in pharmacology and drug studies involving stimulants like amphetamines.

Abstract

Abstract not available from OpenAlex

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