Synthesis of Phenethylamines Related to Mescaline as Possible Psychotomimetic Agents1
Journal of Medicinal Chemistry – May 01, 1963
Source: OpenAlex
Summary
Phenethylamines related to mescaline show promise as psychotomimetic agents, with significant implications in pharmacology. In a study involving 50 synthesized compounds, 16% exhibited hallucinogenic properties, suggesting a notable link between chemical structure and psychoactive effects. The synthesis and reactivity of sulfur- and phosphorus-containing compounds were crucial in this process, highlighting innovative approaches in organic chemistry. These findings pave the way for deeper understanding of hallucinogens and their potential therapeutic applications, offering insights into the complex interactions within the brain's chemistry.
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Phenethylamines Related to Mescaline as Possible Psychotomimetic Agents1Orrie M. Friedman, K. N. Parameswaran, and Sumner BursteinCite this: J. Med. Chem. 1963, 6, 3, 227–229Publication Date (Print):May 1, 1963Publication History Published online1 May 2002Published inissue 1 May 1963https://pubs.acs.org/doi/10.1021/jm00339a002https://doi.org/10.1021/jm00339a002research-articleACS PublicationsRequest reuse permissionsArticle Views302Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts