A Possible Case of Venlafaxine-Induced Stevens-Johnson Syndrome
The Journal of Clinical Psychiatry – October 15, 2004
Source: OpenAlex
Summary
Prolonged psychosis linked to mescaline, a hallucinogen found in peyote, can occur after limited sleep. In a notable case, an individual experienced persistent psychotic symptoms and sleep deprivation lasting over 10 hours following peyote use. This highlights the potential for hallucinogens to induce significant psychological disturbances, especially when combined with sleep loss. Interestingly, symptoms resolved after initiating sleep, suggesting that adequate rest may mitigate drug-induced adverse reactions. Understanding these effects is crucial for psychology and psychiatry, particularly regarding treatment approaches for similar cases.
Abstract
Article AbstractBecause this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.Sir: Psychosis due to sleep deprivation has been frequently reported.1 In hallucinogen use, however, the duration of sleep deprivation is usually limited to a few days, and psychosis is attributed to the direct effects of the hallucinogens on the central nervous system. As a source of hallucinogen, the peyote cactus has been used both as a psychedelic drug and, among many Native Americans in the southwestern United States and Mexico, as a spiritual sacrament. The active ingredient is believed to be mescaline, an alkaloid known to cause visual hallucinations and decreased sleep. These effects subside in a few days, with an average duration of 10 to 12 hours.2 Here, we report a case of prolonged peyote-triggered psychosis and sleep deprivation that was resolved by sleep initiation.