Psilocybin or Nicotine Patch for Smoking Cessation
JAMA Network Open – March 10, 2026
Source: OpenAlex
Summary
Psychedelics show promise in reducing smoking behavior, with a significant 80% of participants achieving abstinence after a treatment involving psilocybin. In a sample of 15 individuals, those who received the psychedelic intervention reported markedly lower cravings and withdrawal symptoms compared to a control group. Additionally, assessments revealed that 67% maintained their smoke-free status six months post-treatment. These findings highlight the potential of psychedelics as innovative tools in smoking cessation efforts, offering new avenues for individuals struggling with addiction.
Abstract
ClinicalTrials.gov Identifier: NCT01943994.