THE ROLE OF PHARMACEUTICAL CARE IN THE THERAPEUTIC USE OF KETAMINE

Zenodo (CERN European Organization for Nuclear Research)  – December 08, 2025

Source: OpenAlex

Summary

Pharmaceutical care plays a crucial role in the safe use of ketamine, especially during its therapeutic applications for major depression. An analysis of 50 studies revealed that while ketamine is effective for treatment, it carries risks, including adverse effects like dissociation and increased blood pressure in up to 30% of patients. Pharmacists can significantly enhance patient safety by monitoring these effects and providing guidance on proper dosage and adherence. This support is vital, particularly in the context of healthcare challenges faced during the COVID-19 pandemic.

Abstract

The present work aims to analyze the role of pharmaceutical care in the therapeutic use of ketamine, considering its clinical applications, risks, and benefits. This is a bibliographic review research carried out using the PubMed and Scielo databases, as well as books from the health sector library. The analysis focused on the anesthetic ketamine, its indications, side effects, improper recreational use, and how the pharmacist’s role and pharmaceutical care can assist in monitoring patients undergoing ketamine therapies, particularly with regard to safe use, monitoring of adverse effects, guidance on dosage, and adherence to treatment.

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