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Psychedelics and schizophrenia: A mystery in history

Mark Haden, Birgitta Woods, Sarah A. Paschall

Journal of Psychedelic Studies December 2, 2023 Peer reviewed DOI: 10.1556/2054.2023.00277 via OpenAlex

Summary

Lower doses of psychedelics, particularly LSD, may have a beneficial effect on the negative symptoms of schizophrenia, suggesting a complex relationship between psychedelics and this condition. Historical and current research indicates that there are instances where psychedelics might benefit individuals with schizophrenia.

Study at a glance

Design analysis
Population individuals with schizophrenia
Key finding Lower doses of psychedelics appear to have a potential beneficial impact on the negative symptoms of schizophrenia.

Abstract

Abstract This analysis of current and historical research and clinical reports observes that the relationship between psychedelics and schizophrenia is complex and there are reports of psychedelics benefiting this population. Specifically, lower doses of psychedelics (mostly LSD) appear to have a potential beneficial impact on the negative symptoms of schizophrenia.

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