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Beyond Standard Diagnoses: Biosemiotics, Symbol Theory, and the Subjective Lifeworld in Neurology, Psychiatry, and Psychotherapy

Jürgen Kriz

Swiss Archives of Neurology Psychiatry and Psychotherapy June 18, 2026 DOI: 10.3390/sanpp176010005 via OpenAlex

Summary

Standard diagnostic categories like the ICD and DSM were created as a practical compromise between competing schools in psychiatry, focusing on symptom patterns to improve reliability, communication, and reimbursement. However, this focus misses the complex bodily, personal, interpersonal, and cultural processes underlying human suffering. The article argues that beneath efforts to address this gap lies a fundamental complementarity in human existence: the organismic–biological dimension, based on Jakob von Uexküll's biosemiotics of pre-linguistic meaning-attribution, and the symbolic–cultural dimension, from Ernst Cassirer's philosophy of symbolic forms, involving socially shared symbol systems. Understanding psychopathology and therapy through both complementary perspectives can enrich clinical practice.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Complementarity molecular biology Symbol formal Compromise Lifeworld Psychopathology
Key finding Psychopathology and therapy can be understood more fully when both the organismic–biological and symbolic–cultural dimensions of human existence are taken as genuinely complementary perspectives.

Abstract

Standard diagnostic categories (International Classification of Diseases (ICD) and Diagnostic and Statistical Manual of Mental Disorders (DSM)) were developed as a pragmatic compromise between competing theoretical schools in psychiatry and psychotherapy. Focused on recognizable patterns of symptoms, they produce reliable descriptions and facilitate clinical communication, research, and reimbursement. Such a focus, however, necessarily falls short of the etiological complexity of bodily, personal, interpersonal, and cultural processes that shape human suffering. This article argues that beneath the diversity of approaches seeking to address this gap, a fundamental complementarity emerges—one constitutive of human existence itself: the complementarity between two irreducible ways of being in the world. The first is the organismic–biological dimension, elaborated in Jakob von Uexküll’s biosemiotics: sign-governed, evolutionarily pre-formed processes of meaning-attribution that operate prior to and independent of language. The second is the symbolic–cultural dimension, developed in Ernst Cassirer’s philosophy of symbolic forms: the embedding of human beings in socially created, intersubjectively shared symbol systems through which the world is seen and understood. Although both approaches were published nearly a century ago, this article is not primarily a historical contribution. Rather, it argues that psychopathology and therapy can be understood more fully—and clinical practice enriched—when both dimensions are taken into account as genuinely complementary perspectives.

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