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Phencyclidine Psychosis

Mark L. Richards, Paul J. Perry, Barry I. Liskow

Drug Intelligence & Clinical Pharmacy June 1, 1979 DOI: 10.1177/106002807901300604

Summary

A 20-year-old woman experienced prolonged psychotic behavior after ingesting an illicit powder likely containing phencyclidine. The psychiatric effects of phencyclidine intoxication are reviewed. Treating the toxic phase with psychotropic drugs may not be beneficial. Hospitalization, supportive care, and urine acidification are recommended treatments for phencyclidine-induced toxic psychosis.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population 20-year-old female
Interventions Hospitalization supportive measures urine acidification
Key finding Hospitalization, supportive measures and urine acidification appear to be the treatments of choice for patients experiencing a toxic psychosis caused by phencyclidine.

Abstract

A case of prolonged psychotic behavior is described of a 20-year-old female following the ingestion of an illicitly obtained powder probably containing phencyclidine. The various psychiatric manifestations of phencyclidine intoxications are reviewed. The benefit of treating the toxic phase with psychotropic drugs is questionable. Hospitalization, supportive measures and urine acidification appear to be the treatments of choice for patients experiencing a toxic psychosis caused by phencyclidine.

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