Behavioral thermoregulation in rats during hyperthermia induced by lysergic acid diethylamide
Neuroscience Letters January 1, 1980 Naotoshi Murakami, Yoshihiro Sakai, Shigeki Ooki 9 citations
In rats trained to press a bar to escape radiant heat, intraperitoneal injections of LSD (8-16 micrograms) dose-dependently increased bar-pressing rates. During this increase, rectal temperature rose while tail-skin and selected ambient temperature decreased. The findings suggest LSD-induced hyperthermia results from action on effector pathways rather than an upward resetting of the thermostat.