Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans
Communications Biology September 30, 2024 Pablo Castro, Andrea I. Luppi, Enzo Tagliazucchi et al. 21 citations
Brain activity during unconsciousness, whether from general anaesthesia or slow wave sleep, is dominated by a recurrent functional connectivity pattern primarily mediated by structural connectivity and with a reduced capacity to transition to other patterns. Conscious awareness is characterized by richer brain dynamics measured by entropy and a greater repertoire of connectivity states. These findings suggest that the dynamic exploration of functional connectivity states provides robust and generalizable markers for the state of consciousness across different conditions.