Human Psychopharmacology Clinical and Experimental
July 1, 2015
Stefania Chiappini, Hugh Claridge, John M. Corkery et al.
45 citations
Methoxetamine (MXE), a novel psychoactive substance, was found in eight fatalities in the UK between 2011 and 2013. The median age at death was 27 years; most decedents were White and male. MXE was directly implicated in four deaths and likely contributed to two others, and in seven of eight cases it was used alongside other substances. The report calls for more research into MXE's health effects and toxicity, and for healthcare professionals to be aware of its harms to develop early interventions and reduce poisonings and deaths.
Human Psychopharmacology Clinical and Experimental
May 1, 2017
Barbara Loi, Mire Zloh, Maria Antonietta de Luca et al.
17 citations
4,4'-DMAR ("Serotoni") is a potent stimulant recently linked to multiple fatalities in Europe. Online drug-forum discussions provide technical knowledge about its use, including routes of administration, doses, desired and adverse effects, comparisons with other drugs, combinations, medications used to reverse its action, and harm-reduction advice. A critical review of evidence-based literature together with qualitative data from six website fora reveals that while netnography (social-network web monitoring) has methodological limitations, it can help clarify clinical and psychopharmacological issues for novel psychoactive substances like 4,4'-DMAR, for which scientific knowledge is extremely scarce.