alpha-Ethyltryptamine (alpha-ET) as a discriminative stimulus in rats.
Pharmacology, biochemistry, and behavior October 1, 2006 Richard A Glennon, Tatiana Bondareva, Richard Young
The drug of abuse alpha-ethyltryptamine (alpha-ET) produces a complex internal cue in rats. Male Sprague-Dawley rats were trained to discriminate 2.5 mg/kg alpha-ET from saline. The cue began within 30 minutes and lasted at least 4 hours. When tested with other drugs, the alpha-ET cue fully generalized to the hallucinogen DOM and to PMMA, but only partially generalized (about 40%) to amphetamine, indicating that alpha-ET's effects are not purely stimulant-like.