Discriminative stimulus properties of alpha-ethyltryptamine optical isomers.
Pharmacology, biochemistry, and behavior January 1, 2001 S S Hong, R Young, R A Glennon
The optical isomers of alpha-ethyltryptamine (alpha-ET) produce distinct psychoactive effects in rats. The (-)isomer produced amphetamine-like effects, while the (+)isomer produced hallucinogen-like effects. Both isomers produced effects similar to MDMA and PMMA at comparable doses. The findings suggest that alpha-ET's stimulant character resides primarily with its (-)isomer and its hallucinogenic character with the (+)enantiomer.