Influence of cannabis use on incidence of psychosis in people at clinical high risk
Psychiatry and Clinical Neurosciences April 18, 2023 Lucy Chester, L. Valmaggia, M. Kempton et al.
Cannabis use is associated with an increased risk of developing psychotic disorders among people already at clinical high risk for psychosis. In a prospective study of this population, cannabis use was linked to a higher incidence of psychotic disorders and to more persistent psychotic symptoms, as well as poorer functional outcomes. The findings strengthen evidence that cannabis acts as a risk factor for psychosis, though the direction of causality remains debated.