Associations between regular cannabis use and brain resting-state functional connectivity in adolescents and adults
Journal of Psychopharmacology July 29, 2023 Natalie Ertl, Will Lawn, Claire Mokrysz et al. 17 citations
Regular cannabis use is associated with localized increases in connectivity of the executive control network (ECN), which may reflect adaptive or compensatory changes in response to regular intoxication. Adolescents generally showed weaker connectivity than adults across multiple brain networks, consistent with normal developmental effects. However, there were no significant interactions between age group and cannabis user group, meaning the connectivity changes linked to cannabis use did not differ between adolescents and adults. No associations were found between cannabis use frequency and any connectivity measures.