A rat model of phencyclidine psychosis.
Life sciences January 1, 1994 S Ogawa, S Okuyama, H Araki et al.
Rats given low doses of phencyclidine (PCP) showed impaired performance in water maze and diving tasks: their swimming latencies shortened gradually while diving latencies increased, whereas control rats performed well. No stereotyped behavior or hyperlocomotion was observed. The authors propose that this animal model, using lower PCP doses, may be useful for studying schizophrenia.