Exploring perinatal ketamine for postpartum depression following cesarean section: A systematic review.
PCN reports : psychiatry and clinical neurosciences September 1, 2024 Jaylyn Thompson, David F Lo, Alexis Foschini et al. 1 citation
A review of eight randomized controlled trials examined whether ketamine given during or after cesarean section can reduce postpartum depression. Some trials found that women who received ketamine had lower scores on the Edinburgh Postpartum Depression Scale shortly after delivery—for example, one trial reported a significantly lower score on day 4—while two other trials found no significant difference at 3 days postpartum. The review suggests that ketamine may help prevent or lessen postpartum depression symptoms after cesarean section, but more research is needed to clarify the relationship between dosage and effect.