Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
2 papers in the library · 34 citations · publishing 2024
Mindfulness-based cognitive therapy (MBCT) reduced depression, anxiety, sleep problems, and inflammatory markers (IL-1β, IL-6, IL-8, TNF-α) while increasing mindfulness, self-compassion, and brain-derived neurotrophic factor (BDNF) in college students with major depressive disorder, compared with a wait-list group. Greater daily practice time and more session attendance were linked to larger reductions in depression, anxiety, and sleep difficulties. Completers showed significantly greater improvement than partial attendees, indicating a dose-response effect.
A systematic review and meta-analysis of 23 randomized controlled trials involving 1029 patients with complex regional pain syndrome found that bisphosphonates and ketamine each provide long-term (beyond one month) pain relief, though neither showed statistically significant short-term benefit. Both treatments caused mild adverse events that required no special intervention. Ketamine and bisphosphonates appeared to be the best pharmacological strategies for pain relief in CRPS.