Effect of intraoperative and/or postoperative esketamine administration on preventing postpartum depression: A systematic review and meta-analysis.
Psychiatry research May 1, 2024 Jinping Wang, Hui Liu, Xinchuan Wei 9 citations
A systematic review and meta-analysis of nine randomized controlled trials with 1277 participants found that administering esketamine during or after cesarean delivery significantly reduces the incidence of postpartum depression and lowers Edinburgh Postnatal Depression Scores in the early postoperative period. Esketamine also decreased the occurrence of postoperative nausea and vomiting without affecting other psychiatric symptoms.