Randomized Trial of Ketamine Masked by Surgical Anesthesia in Depressed Patients
medRxiv Preprint Server April 28, 2023 Theresa R. Lii, Ashleigh E. Smith, Josephine R. Flohr et al. 28 citations preprint
Ketamine may have antidepressant properties, but its acute psychoactive effects make it difficult to successfully mask in placebo-controlled trials, complicating the interpretation of study results.