May 16, 2023
William Wong, Kátia C. Andrade, Thomas Andrillon et al.
21 citations
preprint
A new open-access database, DREAM, combines sleep magneto/electroencephalography (M/EEG) recordings with standardized dream reports to enable large-scale neurocognitive research on dreaming. The initial release includes 20 datasets from 561 participants and 2649 awakenings, each with at least 20 seconds of high-frequency M/EEG data and a classification of the subject's experience. Analyses demonstrate that features extracted from EEG can predict whether a person reports having had a conscious experience during both REM and NREM sleep. The database aims to overcome the limitations of small sample sizes and methodological variability in dream research, allowing new questions to be addressed at a scale unattainable by individual labs.
Nature communications
August 13, 2025
William Wong, Rubén Herzog, Kátia Cristine Andrade et al.
10 citations
A new open database, the DREAM database, combines standardized sleep magneto/electroencephalography (M/EEG) recordings with dream reports from 505 participants across 20 datasets, totaling 2,643 awakenings. Each awakening includes at least 20 seconds of high-resolution sleep EEG (≥100 Hz, ≥2 electrodes) and a classification of the sleeper's reported experience. Analyses showed that reports of conscious experiences during sleep can be predicted from objective EEG features in both REM and NREM sleep. The database aims to overcome limitations of small sample sizes and methodological variability in dream research, enabling larger-scale investigations of the neurocognitive basis of dreaming.
bioRxiv Preprint Server
April 12, 2023
Malika S. Datta, Yannan Chen, Shradha Chauhan et al.
6 citations
preprint
Repeated ketamine administration causes opposite effects on dopamine neurons in different brain regions: a decrease in midbrain areas linked to behavior states and an increase in the hypothalamus. It also alters nerve connections to the prefrontal cortex, striatum, and sensory areas. The findings suggest post-transcriptional regulation of structural plasticity. An unbiased whole-brain analysis reveals divergent brain-wide impacts of chronic ketamine on association and sensory pathways.
Perioperative medicine (London, England)
July 23, 2025
Jing Zhang, Zheng Niu, Ting Wang et al.
5 citations
In patients undergoing total laparoscopic hysterectomy, a single low dose of esketamine (0.25 mg/kg) given at anesthesia induction did not improve overall quality of recovery as measured by the QoR-40 questionnaire compared to saline. However, esketamine reduced intraoperative opioid use, stabilized blood pressure and heart rate, shortened time to extubation and recovery room stay, and lowered postoperative pain scores, inflammation, and sleep disturbance without causing adverse effects. Higher education level was associated with better recovery.
Western journal of nursing research
December 1, 2023
Xiangyi Tan, Yuwei Zhang, Yiling Yang et al.
4 citations
A 6-week internet-based self-help mindful self-compassion program for Chinese parents of children with cancer improved self-compassion, reduced re-experiencing of trauma, eased physical depressive symptoms, and enhanced sleep quality. In a pre-post-test study without a control group, 34 parents participated; significant changes were observed in those four areas. Two participants reported distress, with one withdrawing. The findings suggest the program is feasible and beneficial, though future work should address retention.
World Journal of Psychiatry
June 26, 2026
Jia-zhao Zhang, Tian-Tian Wang, Jing Zhang et al.
Schizophrenia involves marked abnormalities in consciousness, particularly in the interplay between implicit and explicit cognitive processing. Evidence from visual masking and mismatch negativity paradigms indicates deficits from preattentive stages to conscious access. Metacognitive impairments in error and source monitoring suggest implicit processing fails to achieve stable explicit representation. These abnormalities are linked to predictive coding errors, thalamocortical dysconnectivity, and aberrant neural synchrony. This framework connects micro-level sensory deficits with macro-level psychotic phenomenology and may guide future transdiagnostic neuromodulatory interventions.