Mindfulness in treatment-seeking adults with comorbid obsessive-compulsive and major depressive disorders: Mediating effects of obsessive beliefs and mental well-being.
Indian journal of psychiatry May 1, 2025 Mohammad Asif Sheikh, Thaddeus Alfonso 1 citation
Mindfulness is linked to reduced symptom severity in adults with both obsessive-compulsive disorder (OCD) and major depressive disorder (MDD), but through different pathways. In 60 treatment-seeking adults with comorbid OCD and MDD, mindfulness was significantly associated with lower OCD and MDD symptoms. For MDD, this effect was mediated by reductions in obsessive beliefs and improvements in mental well-being. However, these mediators did not significantly explain mindfulness's effect on OCD symptoms, suggesting that mindfulness works through distinct mechanisms for each condition and that tailored interventions may be needed.