ELISA Detection of 30 New Amphetamine Designer Drugs in Whole Blood, Urine and Oral Fluid using Neogen®“Amphetamine” and “Methamphetamine/MDMA” Kits
Journal of Analytical Toxicology July 11, 2016 Maria Nieddu, Lucia Burrai, Elena Baralla et al. 22 citations
Thirty new amphetamine designer drugs were tested for cross-reactivity with two commercial immunoassay kits (Neogen® Amphetamine Specific and Methamphetamine/MDMA assays) in whole blood, urine, and oral fluid. For most of the designer drugs, concentrations as high as 10,000 ng/mL failed to produce a positive response. This shows that while the kits work well for their target drugs—amphetamine, methamphetamine, and MDMA—they cannot reliably detect the tested designer drugs in real forensic cases because the required concentrations far exceed those typically found in biological samples.