Internet-purchased ibogaine toxicity confirmed with serum, urine, and product content levels.
The American journal of emergency medicine July 1, 2015 Charles W O'Connell, Roy R Gerona, Matthew W Friesen et al. 16 citations
Ibogaine, a psychotropic indole alkaloid used in some medical subcultures for its anti-addictive properties, can cause serious health risks including altered mental status, ataxia, gastrointestinal distress, ventricular arrhythmias, and sudden death. A 33-year-old man overdosed on ibogaine while attempting to quit heroin, experiencing altered consciousness, tremor, ataxia, nausea, vomiting, and transient QT interval prolongation, which resolved as the substance cleared. Ibogaine was confirmed in his urine and serum, with a peak serum concentration of 377 ng/mL. Nonlinear elimination kinetics and the presence of its active metabolite noribogaine were also observed. This case provides serial serum concentrations and product-confirmed ibogaine toxicity with transient QT interval prolongation.