Intoxication mortelle à l’iboga: quantification de l’ibogaïne et de l’ibogamine dans des racines d’ibogaet dans des prélèvementspost-mortempar CPG-SM/SM
Annales de Toxicologie Analytique January 1, 2012 Cédric Mazoyer, Jérémy Carlier, Michel Péoc’h et al. 2 citations
A 27-year-old man with a history of drug addiction died about twelve hours after ingesting powdered iboga root during a detoxification program. The main alkaloids ibogaine and ibogamine were measured in the powder and in biological fluids collected at the scene and during autopsy. Concentrations in peripheral blood taken at the scene, peripheral blood from autopsy, urine, and gastric fluid ranged from 0.65 to 53.5 µg/mL for ibogaine and 0.05 to 4.34 µg/mL for ibogamine. The powder contained 7.2% ibogaine and 0.6% ibogamine. Additional toxicological tests revealed concurrent use of diazepam and methadone, supporting the conclusion that death resulted from a mixed overdose with ibogaine as the primary toxic agent.