Morbidity involving the hallucinogenic designer amines MDA and 2C-I.
Journal of forensic sciences November 1, 2009 Julia C Drees, Judy A Stone, Alan H B Wu 34 citations
A 39-year-old woman suffered a severe hemorrhagic stroke after using cocaine, MDMA, and 2C-I, a novel designer amine. Multi-targeted LC-MS/MS urine testing detected 2C-I and MDA, but ruled out MDMA. The stroke was caused by an underlying cerebrovascular condition called Moyamoya, exacerbated by substance abuse. Standard clinical confirmation tests often target only amphetamine, methamphetamine, MDMA, and MDA. This case demonstrates the value of broader LC-MS/MS testing to better identify and understand the prevalence and toxic effects of emerging novel amines like 2C-I.