Determination of ibogaine in plasma by gas chromatography--chemical ionization mass spectrometry.
Journal of chromatography. A February 2, 1996 F R Ley, A R Jeffcoat, B F Thomas 18 citations
A new analytical method using gas chromatography-mass spectrometry with a stable-isotope internal standard can measure ibogaine levels in one milliliter of plasma. The technique is selective and sensitive, addressing a gap in quantitative methods that has limited pharmacokinetic and metabolism studies of ibogaine, a naturally occurring alkaloid being considered as a treatment for drug dependence.