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Y Hayasaka

1 paper in the library · 9 citations · publishing 1987

Papers

Gas chromatographic-mass spectroscopic characterisation of the psychotomimetic indolealkylamines and their in vivo metabolites.

Journal of chromatography November 27, 1987 B R Sitaram, L Lockett, M Mcleish et al. 9 citations

A new method combining liquid chromatography with gas chromatography-mass spectrometry provides unequivocal verification of structurally characteristic metabolites of the psychotomimetic indolealkylamines N,N-dimethyltryptamine and 5-methoxy-N,N-dimethyltryptamine. Previously, metabolite identity was confirmed using multiple analytical techniques including multidimensional liquid chromatography and stop-flow spectroscopic analysis. The described approach enables separation, characterization, and quantitation of metabolites formed both in vitro and in vivo.