Ascorbic acid antagonizes the behavioural effects of LSD in cats.
The Journal of pharmacy and pharmacology December 1, 1985 M E Trulson, T Crisp, L J Henderson
Giving cats ascorbic acid before LSD or apomorphine blocked certain behavioral effects, but it did not block the effects of 5-methoxy-N,N-dimethyltryptamine. These results suggest that the behaviors caused by LSD and apomorphine involve both serotonin and dopamine receptors, and that ascorbic acid can change how LSD acts at dopamine receptors.