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Fedor Panov

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, 1000 10th Ave, New York, NY 10019, USA.

3 papers in the library · 9 citations · publishing 2023-2025

Papers

Intracranial substrates of meditation-induced neuromodulation in the amygdala and hippocampus.

Proceedings of the National Academy of Sciences of the United States of America February 11, 2025 Christina Maher, Lea Tortolero, Soyeon Jun et al. 7 citations

Loving-kindness meditation, which involves directing thoughts of goodwill toward oneself and others, alters neural activity in the amygdala and hippocampus. In first-time meditators with implanted brain-recording devices, the practice increased gamma-band (30 to 55 Hz) power and changed the duration of beta (13 to 30 Hz) and gamma oscillatory bursts in both regions. These changes were specific to periodic features of neural activity, not aperiodic ones. The findings suggest that even novice meditation can modulate limbic brain activity linked to emotional regulation and mood disorders.

Intracranial substrates of meditation-induced neuromodulation in amygdala and hippocampus

bioRxiv Preprint Server May 10, 2024 Christina Maher, Lea Tortolero, Daniel D. Cummins et al. 1 citation preprint

Loving-kindness meditation (LKM) increases gamma power and alters the duration of beta and gamma oscillatory bursts in the amygdala and hippocampus of first-time meditators. These changes were specific to periodic features of neural activity, not aperiodic ones. The findings reveal how LKM modulates limbic brain activity, offering insight into the neural basis of meditation's effects on emotional regulation and well-being.

36 Impact of Neuropsychological Performance and Anxiety on Meditation in Drug Resistant Epilepsy (DRE) Patients Implanted with a Responsive Neurostimulation (RNS) Device

Journal of the International Neuropsychological Society November 1, 2023 Adam E. Saad, Lea Tortelero, Sloane Sheldon et al. 1 citation

In patients with drug-resistant epilepsy who have a responsive neurostimulation (RNS) device implanted, a meditation protocol reduced anxiety symptoms. Ten patients completed loving-kindness and focal awareness meditation sessions while intracranial recordings were taken. Pre-surgery neuropsychological tests showed elevated anxiety and depression, with frontal or frontotemporal deficits in 80% of patients. A negative correlation was found between pre-meditation anxiety and self-reported depth of meditation engagement. Across all sessions, anxiety levels decreased after meditation. The findings suggest that meditation can help manage anxiety in this population, and integrating neuropsychological and neuropsychiatric evaluations may improve treatment.