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Smaranda Leu-Semenescu

Service des Pathologies du Sommeil, National Reference Centre for Narcolepsy and Rare Hypersomnias, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.

3 papers in the library · 171 citations · publishing 2021-2025

Papers

Real-time dialogue between experimenters and dreamers during REM sleep.

Current biology : CB April 12, 2021 Karen R Konkoly, Kristoffer Appel, Emma Chabani et al. 126 citations

People who are asleep and having a lucid dream—aware that they are dreaming—can perceive questions from an experimenter and answer them in real time using eye movements and facial muscle contractions. In a study of 36 individuals during REM sleep, including frequent lucid dreamers, a novice, and a patient with narcolepsy, participants performed perceptual analysis of new information, held information in working memory, computed simple answers, and gave volitional replies. Correct answers occurred on 29 occasions across 6 individuals, documented by four independent laboratories. This two-way communication channel allows real-time interrogation of dream cognition and characteristics.

Are sleep paralysis and false awakenings different from REM sleep and from lucid REM sleep? A spectral EEG analysis.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine April 1, 2021 Greta Mainieri, Jean-Baptiste Maranci, Pierre Champetier et al. 40 citations

Sleep paralysis and false awakenings are intermediate states between REM sleep and wakefulness. In a sleep-laboratory study of five participants, polysomnography recordings captured five sleep-paralysis episodes and two false awakenings. During sleep paralysis, 70.8% of 3-second mini-epochs showed theta brain waves (compared to 89.7% in normal REM sleep and 21.2% in wakefulness), 93.8% had chin-muscle atonia (vs 89.7% in REM and 33.3% in wakefulness), and 6.9% contained rapid eye movements (vs 11.9% in REM and 8.1% in wakefulness). The electroencephalography spectrum during sleep paralysis was intermediate between wakefulness and REM sleep for alpha, theta, and delta frequencies, while beta frequencies matched normal REM sleep.

Talking to sleepwalkers? Response to communication efforts in disorders of arousals.

Sleep February 10, 2025 Yannis Idir, Régis Lopez, Amélie Barbier et al. 5 citations

Disorders of arousal (DoA) episodes, such as sleepwalking, are not a uniform state but involve varying levels of consciousness and responsiveness. In a retrospective questionnaire, 81% of 61 adult patients reported occasional conversations during episodes. Auditory stimulation during N3 sleep triggered episodes in only 7 of 157 trials, and only one patient indirectly responded to verbal prompts. Analysis of 364 home video-recorded episodes from 19 patients found 37 instances of discussion with a bed partner. Patients' ongoing mental content influenced their responses and perception of the outside world. These findings highlight limitations in current diagnostic criteria for DoA.