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Carolina Seybert

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisbon, Portugal; ISPA-Instituto Universitário Ciências Psicológicas, Sociais e da Vida, Lisbon, Portugal.

4 papers in the library · 53 citations · publishing 2021-2025

Papers

Quality of reporting on psychological interventions in psychedelic treatments: a systematic review.

The lancet. Psychiatry January 1, 2025 Carolina Seybert, Nina Schimmers, Lucio Silva et al. 26 citations

Reporting on the psychological intervention component of psychedelic-assisted psychotherapy is mostly incomplete and inconsistent across studies, limiting replicability and clinical translation. A systematic review of 45 original studies on psilocybin, MDMA, LSD, or ayahuasca for mental disorders found that descriptions of psychotherapy varied widely and completeness of information was generally low, based on an adapted Template for Intervention Description and Replication checklist. Studies involving MDMA showed more homogeneous psychotherapy and more procedural details. Improved reporting on psychological interventions would support replicability, generalisability, and accurate interpretation of research, as well as enhance feasibility and safety of future clinical research and real-world implementation.

DOI: 10.1016/s2215-0366(24)00333-x Full text Psychedelic therapy Mental health treatment Therapeutic protocols Clinical research +1

Reply: Variability in motor threshold

Brain stimulation October 5, 2021 Gonçalo Cotovio, Albino J. Oliveira‐maia, Carter Paul et al. 3 citations

Transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal cortex does not reduce depressive symptoms more than sham stimulation in patients with treatment-resistant depression. In a randomized controlled trial, both active and sham tDCS groups showed similar improvements in depression scores over six weeks, with no significant difference between them. The findings suggest that tDCS, as administered in this protocol, is not effective as a standalone treatment for this population.

DOI: 10.1016/j.brs.2021.09.012 Scopus Depression economics Psychology Randomized controlled trial +7