Rumination and Self-Compassion Moderate Mindfulness-Based Cognitive Therapy for Patients With Recurrent and Persistent Major Depressive Disorder: A Controlled Trial.
Depression and anxiety January 1, 2024 Jelle Lubbers, Dirk E M Geurts, Philip Spinhoven et al. 10 citations
Mindfulness-based cognitive therapy (MBCT) added to treatment as usual reduced depressive symptoms and overall functional impairment more than treatment as usual alone in patients with persistent or recurrent major depressive disorder, with medium and small effect sizes respectively. The therapy worked better for those who started with higher levels of rumination and perseverative thinking and lower levels of self-compassion; these traits moderated the treatment's effects. No mediators of MBCT's effects were identified, as the therapy did not change the assessed potential mediators by mid-treatment. Allocating MBCT based on patients' rumination and self-compassion levels could make symptom reduction more efficient.