Depression and anxiety
January 1, 2008
Marcel O Bonn-Miller, Michael J Zvolensky, Amit Bernstein et al.
29 citations
Among 149 young adult marijuana users, those who both used marijuana frequently (past 30 days) and reported using it to cope with negative emotions had the highest levels of anxious arousal, agoraphobic cognitions, and worry. This pattern held after accounting for cigarettes, alcohol, and years of marijuana use. No similar interaction was found for depressive symptoms, suggesting the link is specific to anxiety rather than depression.
Depression and anxiety
January 1, 2024
Luise Pruessner, Christina Timm, Julia Kalmar et al.
22 citations
Mindfulness helps reduce depression and anxiety symptoms by improving how people regulate their emotions. In 162 patients receiving cognitive-behavioral therapy, decreases in rumination and increases in reappraisal and acceptance explained mindfulness's link to fewer depressive symptoms, while reductions in avoidance explained its link to fewer anxiety symptoms. Adding a brief mindfulness exercise at the start of each therapy session did not change these effects. The findings suggest distinct emotional pathways through which mindfulness alleviates depression versus anxiety.
Depression and anxiety
January 1, 2024
Ludovic Samalin, Lila Mekaoui, Maud Rothärmel et al.
16 citations
In a French real-world study of 157 patients with treatment-resistant depression who began esketamine nasal spray, most discontinued treatment within about 19 weeks. After one month, 40% of those still on the drug showed clinical response and 20% achieved remission. Adverse events occurred in 69% of patients, with serious events in 17%. The findings align with earlier clinical trials, confirming esketamine's role in treating treatment-resistant depression.
Depression and anxiety
January 1, 2024
Jelle Lubbers, Dirk E M Geurts, Philip Spinhoven et al.
10 citations
Mindfulness-based cognitive therapy (MBCT) added to treatment as usual reduced depressive symptoms and overall functional impairment more than treatment as usual alone in patients with persistent or recurrent major depressive disorder, with medium and small effect sizes respectively. The therapy worked better for those who started with higher levels of rumination and perseverative thinking and lower levels of self-compassion; these traits moderated the treatment's effects. No mediators of MBCT's effects were identified, as the therapy did not change the assessed potential mediators by mid-treatment. Allocating MBCT based on patients' rumination and self-compassion levels could make symptom reduction more efficient.
Depression and anxiety
January 1, 2023
Thomas H Nassif, Ian A Gutierrez, Carl D Smith et al.
7 citations
A mindfulness and yoga intervention for U.S. Army soldiers in Basic Combat Training reduced positive screens for depression and sleep problems more than standard training alone. Depression screens fell 12.6% in the intervention group versus 7.2% in the control group. Sleep problems decreased 1.4% in the intervention group but increased 2.0% in the control group. Anxiety screens decreased over time in both groups with no significant difference between them. The findings suggest that mindfulness and yoga may help sustain mental health during high-stress military training.
Depression and anxiety
January 1, 2025
Camille Piguet, Zeynep Celen, Ben Meuleman et al.
2 citations
A mindfulness-based intervention for young adolescents from the general population did not reduce stress, anxiety, depressive symptoms, or improve emotion regulation, despite being very well accepted and receiving high satisfaction ratings. In a randomized controlled trial, 70 adolescents aged 13 to 15 years were assigned to an 8-week mindfulness program or a waiting list. Self-reported measures showed no benefit on any symptom or affect measure. Trait mindfulness was linked to lower stress and anxiety. Individual responses varied widely. The findings align with evidence that mindfulness programs may be more effective for clinical than nonclinical groups.
Depression and anxiety
January 1, 2025
Julia Fabienne Sandkühler, Fabian Kahl, Magda Zena Sadurska et al.
2 citations
In a large trial with over a thousand participants, twelve different psychotherapeutic exercises delivered through the Mind Ease app each reduced anxiety more than either a reading control or a no-activity control. The exercises included cognitive restructuring, diaphragmatic breathing, gratitude practice, positive expressive writing, progressive muscle relaxation, guided imagery, and several mindfulness techniques. Effect sizes ranged from medium to very large, with mindfulness exercises generally showing larger effects than cognitive restructuring. Differences between exercises were substantial, with 42% of pairwise comparisons reaching statistical significance. The findings suggest that a variety of brief, app-based exercises can provide immediate anxiety relief.