Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; Departamento de Psiquiatría, Centro Investigación Biomedica en Red de Salud Mental (CIBERSAM), Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain; TiPP Program Department of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Lausanne, Switzerland. Electronic address: laluisalameda@gmail.com.
2 papers in the library · 15 citations · publishing 2025
Mindfulness-based interventions (MBIs), including Mindfulness-Based Cognitive Therapy, Acceptance and Commitment Therapy, and Dialectical Behavioural Therapy, are effective at reducing depressive symptoms across a range of psychiatric disorders. A systematic review and meta-analysis of 35 randomized controlled trials covering 12 diagnostic categories found that these interventions produced significant effect sizes compared to active control conditions. The findings suggest that MBIs can serve as a cost-effective, transdiagnostic tool for treating depressive symptoms not only in depressive disorders but across mental health conditions.
Childhood trauma, especially emotional and physical abuse, is strongly linked to paranoia, and cannabis use amplifies that effect. In a survey of 4,736 adults, those who experienced childhood trauma reported higher paranoia, and weekly cannabis use—measured in standard THC units—also predicted greater paranoia. Cannabis use partially mediated the link between trauma and paranoia, though trauma itself had a much larger direct effect. The findings suggest that assessing both trauma history and cannabis exposure in standard THC units could improve risk detection and guide interventions for people with childhood trauma.