Effects of virtual reality mindfulness on cognition and well-being in ALS: A randomized trial protocol.
Contemporary clinical trials May 1, 2025 Juliette Faure-De Baets, Jeremy Besnard, Frédéric Banville et al. 3 citations
A randomized controlled trial will test whether virtual-reality-based mindfulness training improves quality of life more than traditional mindfulness for people with amyotrophic lateral sclerosis (ALS). Forty-six participants will be randomly assigned to an eight-week mindfulness program delivered either through VR or in a conventional format. The primary outcome is quality of life, measured by the ALS-Specific Quality of Life Scale; secondary outcomes include cognitive function, anxiety, depression, behavioral changes, and mindfulness propensity, assessed at baseline, after the intervention, and three months later. The study also examines VR usability and accessibility challenges. If effective, VR mindfulness could make psychological support more accessible for patients with severe physical limitations.