CURRENT STATE OF PSILOCYBIN-ASSISTED THERAPY IN MOOD DISORDERS
Psychiatria Danubina July 17, 2024 Astrid Kaiserman, Charles Kornreich, Laetitia Vanderijst 1 citation
Psychedelics are being re-evaluated for therapeutic use, with psilocybin-assisted therapy (PAT) showing positive effects on depression and anxiety in patients with life-threatening diseases. PAT appears safe and feasible in clinical settings, with preliminary evidence of immediate and partially sustained improvements in mood symptoms. One trial found no significant difference in efficacy between PAT and selective serotonin reuptake inhibitors. The studies reviewed suggest PAT induces neuroplasticity and may help change inflexible thinking patterns. However, larger, more diverse studies with better controls for expectancy are needed to confirm these promising results.