Mindfulness-Based Cognitive Therapy for Treatment-Resistant Depression: A protocol for systematic review and meta-analysis.
PloS one January 1, 2024 Michele F Rodrigues, Larissa Junkes, Jose Appolinario et al. 5 citations
This systematic review protocol outlines a planned investigation into whether Mindfulness-Based Cognitive Therapy (MBCT) effectively reduces depressive symptoms in adults with Treatment-Resistant Depression (TRD) compared to standard care or other active treatments, and whether its safety profile is comparable. The review will search multiple databases and trial registries for randomized clinical trials and quasi-experimental studies without language or date restrictions. Study quality will be assessed with the Cochrane Risk of Bias Tool, and confidence in the evidence will be appraised using GRADE methodology. The protocol was registered in PROSPERO in April 2023.