Human Psychopharmacology Clinical and Experimental
May 1, 2017
Leigh Coney, Larissa J. Maier, Jason Ferris et al.
18 citations
Most people who use LSD analogues (AL-LAD, 1P-LSD, ETH-LAD) have also tried LSD, and in the UK and US a higher proportion reported using analogues in the past year than LSD alone. Users described the effects as psychedelic, obtained the drugs online, and took them orally. The time to peak effect (2 hours) and duration (8 hours) were similar to LSD, but ratings for pleasurable high, strength, comedown, urge to use more drugs, value for money, and risk of harm were all significantly lower for the analogues compared with LSD. The authors suggest future studies should confirm these findings with chemical testing and dose measurement.
Addiction (Abingdon, England)
January 1, 2025
Leigh Coney, Amy Peacock, Daan van der Gouwe et al.
8 citations
Drugs sold on cryptomarkets are not uniformly higher in quality than those bought offline. For MDMA tablets, MDMA powder, cocaine, and LSD, the advertised substance is more likely to be present when sourced from cryptomarkets. Strength is higher for cryptomarket MDMA powder, cocaine, and methamphetamine, but lower for MDMA tablets and amphetamine. Adulteration is less likely in cryptomarket MDMA powder and cocaine, but more likely in amphetamine and LSD. Cocaine from cryptomarkets also has fewer adulterants. The relationship between source and drug quality depends on the specific substance and market dynamics.
The International journal on drug policy
January 1, 2024
Leigh Coney, Amy Peacock, Aili Malm et al.
2 citations
People who buy MDMA, cocaine, or LSD from cryptomarkets are more likely to have no drug-using social network and to report adverse events requiring medical treatment. Among over 23,000 respondents from more than 70 countries in the 2018 Global Drug Survey, adverse events were low overall (5.2%). After controlling for age, gender, and frequency of use, recent cryptomarket use was associated with a higher likelihood of having no drug-using network for each drug. It was also linked to increased odds of adverse events for cocaine (adjusted odds ratio 1.70) and LSD (adjusted odds ratio 1.58). For those with a network larger than one person, cryptomarket use was still associated with more adverse LSD events. The findings suggest cryptomarket use may increase drug-related harm, but the complex mechanisms require further study.