Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies.
Journal of neural transmission (Vienna, Austria : 1996) May 1, 2024 Fahd François Hilal, Jerome Jeanblanc, Chloé Deschamps et al. 8 citations
A review of preclinical studies in animal models examines two emerging approaches for alcohol use disorder: psychedelics and epigenetic drugs (epidrugs). Both treatments show potential benefits for reducing alcohol drinking, seeking, motivation, and relapse. Because psychedelics and epidrugs may share common and complementary mechanisms of action, there is an opportunity for exploring synergies between these approaches and their parallel effectiveness in treating AUD and associated psychiatric conditions.