A randomized controlled trial of mindfulness-based cognitive therapy for major depressive disorder in undergraduate students: Dose- response effect, inflammatory markers and BDNF.
Psychiatry research January 1, 2024 Wei Liu, Jing Yuan, Yun Wu et al. 19 citations
Mindfulness-based cognitive therapy (MBCT) reduced depression, anxiety, sleep problems, and inflammatory markers (IL-1β, IL-6, IL-8, TNF-α) while increasing mindfulness, self-compassion, and brain-derived neurotrophic factor (BDNF) in college students with major depressive disorder, compared with a wait-list group. Greater daily practice time and more session attendance were linked to larger reductions in depression, anxiety, and sleep difficulties. Completers showed significantly greater improvement than partial attendees, indicating a dose-response effect.