Psilocybin, found in psilocybe mushrooms, has low toxicity and addiction risk, but negative outcomes from its use are not well understood. Analyzing 346 self-reports from an online platform using textual analysis software, the study identified four main clusters: thinking distortions, emergencies, perceptual alterations, and substance administration. Bad trips were more frequent among female users and linked to thinking distortions. Using multiple doses in one session or combining psilocybin with other substances was associated with long-term negative outcomes, while single high doses of mushrooms were linked to medical emergencies. These findings can inform harm-reduction efforts.
People who currently use ayahuasca/DMT, psilocybe mushrooms, LSD, cannabis, or MDMA/ecstasy score higher on nature relatedness than those who have never used these substances. After accounting for sociodemographic factors, only current and past use of ayahuasca/DMT remained positively associated with nature relatedness. Among those who reported an intention to use psilocybe mushrooms in the future, that intention was also linked to higher nature relatedness. The findings suggest that classic serotonergic psychedelics may have a unique relationship with nature relatedness, but the cross-sectional design cannot establish causation.