Rediscovering Psilocybin as an Antidepressive Treatment Strategy
Pharmaceuticals September 28, 2021 René Zeiss, Maximilian Gahr, Heiko Graf 17 citations
Psilocybin shows promise as an antidepressant for major depressive disorder, with studies reporting high treatment effect sizes. However, the exact mechanism by which it alleviates depression and the role of the psychedelic experience itself remain unclear. No severe adverse events were observed in the reviewed studies, but results are considered preliminary due to limitations. Several safety and utility questions require further research.