Neural correlates of the personality factor openness before and after psilocybin-therapy to depressed patients
Zenodo (CERN European Organization for Nuclear Research) August 31, 2019 Manca Peskar
In treatment-resistant depression, openness to experience and its neural correlates were examined before and after a psilocybin-assisted intervention. The study aimed to extend personality neuroscience findings from healthy individuals to depressed populations and to uncover neural mechanisms that might mediate clinical improvements. The results suggest that changes in openness are linked to specific brain activity patterns, potentially underlying therapeutic benefits.