Psychoactives
April 22, 2025
Kerem Kemal Soylemez, Emma Marie de Boo, Joanne Lusher
7 citations
Psychedelic substances like LSD, psilocybin, and MDMA show promise for treating depression, anxiety, and addiction when administered in controlled settings with psychological support. They can induce profound psychological insights that lead to long-lasting positive changes in mood, cognition, and behavior. However, ethical, social, and regulatory challenges across different countries influence societal beliefs about their efficacy and use. The review calls for further research to develop standardized administration protocols and understand societal implications and long-term outcomes, highlighting the need for rigorous scientific inquiry and ethical considerations.
Psychoactives
September 2, 2025
Kerem Kemal Soylemez, Emma Marie de Boo, Aysil Susuzlu et al.
2 citations
A narrative review of existing literature examines the potential of psychedelics such as psilocybin and LSD for treating dementia, a progressive neurodegenerative disease characterized by cognitive decline, memory loss, and behavioral changes. Psychedelics alter perception, mood, and cognition by affecting serotonin receptors and may promote neuroplasticity, reduce neuroinflammation, and enhance cognitive flexibility. These effects could slow disease progression and improve quality of life for patients, who often experience emotional distress, and may also help prevent dementia by fostering brain health. The review raises significant safety and ethical concerns and aims to critically raise awareness on the topic.
World Journal of Advanced Research and Reviews
March 7, 2025
Kerem Kemal Soylemez, Emma Marie de Boo, Coral Yaron Shoklander et al.
2 citations
People who have never used psychedelics express mixed views about their use in mental health treatment, acknowledging potential benefits but also voicing concerns about safety and control. Interviews with eight participants recruited through snowball and convenience sampling revealed four themes: Imbalance within Control Dynamics, Therapeutic Efficacy, Across Generations and Borders, and Growing Awareness. Age and culture appear to shape these perceptions. While participants recognize that psychedelics could help treat mental health conditions, they remain apprehensive about their application in controlled settings.