Neuroplasticity and Neuro-Generation: The Promise of Psychedelics in Dementia Care
Psychoactives September 2, 2025 Kerem Kemal Soylemez, Emma Marie de Boo, Aysil Susuzlu et al. 2 citations
A narrative review of existing literature examines the potential of psychedelics such as psilocybin and LSD for treating dementia, a progressive neurodegenerative disease characterized by cognitive decline, memory loss, and behavioral changes. Psychedelics alter perception, mood, and cognition by affecting serotonin receptors and may promote neuroplasticity, reduce neuroinflammation, and enhance cognitive flexibility. These effects could slow disease progression and improve quality of life for patients, who often experience emotional distress, and may also help prevent dementia by fostering brain health. The review raises significant safety and ethical concerns and aims to critically raise awareness on the topic.