Psilocybin-Assisted Psychotherapy for Chronic Somatoform Pain Disorder: A Case Report
Psychoactives September 1, 2025 M Mercier, Cédric Mabilais, Vasileios Chytas et al.
A patient with persistent somatoform pain disorder and recurrent depressive disorder underwent four sessions of psilocybin-assisted psychotherapy. The intervention was associated with reduced negative impact of pain on daily life, increased pain acceptance, improved quality of life, and fewer depressive symptoms. The case suggests that psychedelics combined with psychotherapy may offer a novel approach to chronic pain treatment, though controlled studies are needed.