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Dingle Spence

Hope Institute Hospital, Kingston, Jamaica.

2 papers in the library · 9 citations · publishing 2023-2025

Papers

Applying Key Lessons from the Hospice and Palliative Care Movement to Inform Psychedelic-Assisted Therapy.

Psychedelic medicine (New Rochelle, N.Y.) September 1, 2023 Megan Miller, William E Rosa, Alden Doerner Rinaldi et al. 9 citations

Psychedelic-assisted therapy (PAT) and hospice/palliative care share deep synergies that could help integrate PAT into mainstream health systems. Hospice and palliative care, though now evidence-based standards, began as grassroots movements. Their holistic, interdisciplinary, relationship-centered, and spiritually attuned models offer practical lessons for scaling human-centered PAT. Key aspects include interdisciplinary care, holistic views of health, bearing witness to suffering, customized care, decentralized models, generalist/specialist competencies, fostering spirituality, and growth from community organizations to mature systems. Conversely, PAT's radical emphasis on meaning-making and relationship may also innovate hospice and palliative care.

Psilocybin

May 1, 2025 Jessi Humphreys, Lou Lukas, Yvan Beaussant et al.

Psilocybin, a psychoactive compound from over 200 mushroom species, has a long history in Indigenous sacred rituals. It binds to serotonin receptors, activating the serotonergic system to promote neuroplasticity, which helps individuals derive meaning from psychedelic experiences. Evidence suggests benefits for major depressive disorder, anxiety disorders, existential suffering, and substance use disorders. Dosing ranges from low psycholytic to high psychoactive levels. While physiological harm to humans appears low, further research is needed on cardiac and neurological safety in diverse and vulnerable groups. Legal access is expanding through decriminalization, legalization, and right-to-try approaches, varying by region.